How Long to Cook a 21-Pound Turkey in the Oven at 325°F?

Learn the ideal cooking time and temperature for a 21-pound turkey in the oven, plus tips to ensure it stays juicy and safe.

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Cooking a 21-pound turkey in an oven set to 325°F (165°C) typically takes about 4 to 4.5 hours if it's unstuffed, and 4.5 to 5 hours if it's stuffed. Ensure the turkey reaches an internal temperature of 165°F (74°C) in the thickest part of the thigh for safety. For the best results, baste the turkey every 45 minutes and cover the breast with foil if it begins to brown too much. Rest your turkey for 20-30 minutes before carving to lock in juices.

FAQs & Answers

  1. What internal temperature should a cooked turkey reach? A cooked turkey should reach an internal temperature of 165°F (74°C) in the thickest part of the thigh to ensure it is safe to eat.
  2. Do I need to stuff a 21-pound turkey before cooking? Stuffing is optional. If you stuff the turkey, expect to add about 30 minutes to the cooking time to ensure the stuffing also reaches a safe temperature.
  3. How long should I let the turkey rest before carving? Rest the turkey for 20-30 minutes after cooking to allow the juices to redistribute, resulting in a moister and more flavorful bird.
  4. Should I baste the turkey while it cooks? Yes, basting the turkey every 45 minutes helps maintain moisture. Covering the breast with foil if it browns too much is also recommended.

Watch More

For more helpful cooking tips and recipes, check out our guides on how to prepare perfect Thanksgiving side dishes and carving the turkey like a pro to impress your guests.

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