What is the False Negative Rate of Non-Invasive Prenatal Testing (NIPT)?
Discover the false-negative rate of NIPT and why confirmatory tests are vital for accurate prenatal results.
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Non-Invasive Prenatal Testing (NIPT) is highly accurate but not flawless. The false-negative rate can be influenced by multiple factors, such as the quality of the sample and specific conditions being tested. Generally, the false-negative rate for NIPT is low, around 0.2% to 1%. It is crucial to follow up with confirmatory tests, like amniocentesis or chorionic villus sampling (CVS), to ensure accurate results and make informed decisions about pregnancy management.
FAQs & Answers
- What factors influence the false-negative rate of NIPT? The false-negative rate of NIPT can be influenced by factors such as the quality of the sample and the specific conditions being tested.
- Is NIPT a definitive test? No, while NIPT is highly accurate, it is not definitive. Follow-up confirmatory tests like amniocentesis are recommended.
- How accurate is Non-Invasive Prenatal Testing? NIPT generally has a low false-negative rate, around 0.2% to 1%, making it a highly reliable option for prenatal screening.
- What follow-up tests are recommended after NIPT? Confirmatory tests such as amniocentesis or chorionic villus sampling (CVS) are recommended to ensure accurate results.