Why Can NIPT Test Results Be Incorrect? Understanding Causes and Next Steps

Learn why NIPT test results can be wrong, factors affecting accuracy, and recommended steps for reliable prenatal screening outcomes.

Published

Video transcript

NIPT tests can be wrong due to various factors, including low fetal DNA fraction, maternal DNA contamination, or technical errors. To reduce the chance of inaccuracies, ensure the test is conducted at the recommended gestational age (10 weeks or later) and consider repeat testing or follow-up diagnostic tests (like amniocentesis) if results are unexpected. Discussing possible outcomes and limitations with a healthcare professional before testing is important.

Questions and answers

  1. What factors cause NIPT test results to be incorrect?

    NIPT results can be inaccurate due to low fetal DNA fraction in the blood sample, contamination with maternal DNA, or technical laboratory errors.

  2. When should I have an NIPT test for the most accurate results?

    For optimal accuracy, NIPT should be conducted at 10 weeks of gestation or later to ensure sufficient fetal DNA is present.

  3. What should I do if my NIPT test results are unexpected or unclear?

    If results are unexpected, consider repeat testing or follow-up diagnostic procedures like amniocentesis after consulting a healthcare professional.