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Who Is Most Likely to Have a Child with Trisomy 21 (Down Syndrome)?

Discover why older maternal age increases the risk of Trisomy 21 (Down syndrome) and learn about key risk factors for this genetic condition.

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Video transcript

Individuals with older maternal age are most likely to have a child with Trisomy 21, commonly known as Down syndrome. The likelihood increases significantly after age 35. However, Trisomy 21 can occur in any pregnancy, regardless of maternal age.

Questions and answers

  1. What is Trisomy 21?

    Trisomy 21, commonly known as Down syndrome, is a genetic disorder caused by an extra copy of chromosome 21.

  2. How does maternal age affect the risk of having a child with Trisomy 21?

    The risk of having a child with Trisomy 21 increases significantly after the age of 35 in mothers.

  3. Can younger mothers have a child with Down syndrome?

    Yes, Trisomy 21 can occur in any pregnancy regardless of maternal age, though it is less common in younger mothers.

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For more information on genetic conditions and prenatal health, explore our videos on chromosomal abnormalities, prenatal screening methods, and how maternal age influences pregnancy outcomes.