What is the Gold Standard for GFR Testing?
Discover the gold standard for GFR testing, including the measured GFR and its advantages over estimated methods.
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The gold standard for GFR test is the measured GFR (mGFR). This is typically determined by using exogenous filtration markers like inulin, iothalamate, or iohexol. The procedure involves injecting these substances and measuring their clearance from the bloodstream. Though highly accurate, mGFR is more complex and expensive than the commonly used estimated GFR (eGFR), which uses serum creatinine levels for estimation.
FAQs & Answers
- What is mGFR? mGFR, or measured Glomerular Filtration Rate, is a precise test that determines kidney function using exogenous filtration markers.
- Why is eGFR commonly used? eGFR, or estimated GFR, is commonly used because it is simpler and less expensive, relying on serum creatinine levels for estimation.
- What markers are used for mGFR testing? Markers used for mGFR testing include inulin, iothalamate, and iohexol, which help measure the clearance of substances from the bloodstream.
- How does GFR testing affect kidney health? GFR testing is crucial for assessing kidney health, helping to diagnose conditions, monitor progression, and guide treatment options.