Understanding Toxic Concentrations of Metformin: Symptoms and Risks

Learn what constitutes a toxic concentration of metformin and the symptoms of overdose, including lactic acidosis.

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A toxic concentration of metformin typically exceeds 5 micrograms per milliliter in the blood. Such levels can lead to lactic acidosis, a serious condition characterized by the buildup of lactic acid. Immediate medical attention is crucial if an overdose is suspected or symptoms of toxicity occur, such as rapid breathing, muscle pain, or extreme tiredness.

FAQs & Answers

  1. What are the symptoms of metformin toxicity? Symptoms of metformin toxicity include rapid breathing, muscle pain, extreme tiredness, and other signs of lactic acidosis, which requires immediate medical attention.
  2. What should I do if I suspect a metformin overdose? If you suspect a metformin overdose, seek immediate medical attention as it can lead to serious health complications such as lactic acidosis.
  3. What is lactic acidosis and how is it related to metformin? Lactic acidosis is a serious condition characterized by an excess of lactic acid in the body, which can occur if toxic levels of metformin are present in the blood.
  4. What is the safe concentration of metformin in the blood? The safe concentration of metformin in the blood is typically below 5 micrograms per milliliter; exceeding this level raises the risk of toxicity and lactic acidosis.