How to Manually Calculate eGFR: A Step-by-Step Guide

Learn how to manually calculate eGFR using the CKD-EPI formula with essential patient data.

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To manually calculate eGFR: First, gather the patient's serum creatinine level (mg/dL), age, gender, and ethnicity. Use the MDRD or CKD-EPI formula. For CKD-EPI: eGFR = 141 × min(Scr/κ, 1)^α × max(Scr/κ, 1)^-1.209 × 0.993^age × 1.018 [if female] × 1.159 [if African American], where κ and α are constants based on gender.

FAQs & Answers

  1. What is the eGFR used for? The eGFR, or estimated Glomerular Filtration Rate, is used to assess kidney function and determine the stage of kidney disease.
  2. What factors affect eGFR calculations? Factors including serum creatinine level, age, gender, and ethnicity can significantly impact eGFR calculations.
  3. How do the CKD-EPI and MDRD formulas differ? The CKD-EPI formula is typically more accurate at estimating eGFR compared to the MDRD formula, especially at higher eGFR levels.
  4. Why is it important to monitor eGFR? Regularly monitoring eGFR helps detect changes in kidney function early, which is critical for timely intervention in kidney disease.

Watch More

For further insight into kidney health, check out our additional videos on serum creatinine levels and the significance of eGFR in clinical practice.

  1. Which GFR Calculator is the Most Accurate for Kidney Function Assessment? Discover the most accurate GFR calculator for kidney function monitoring. Explore CKD-EPI’s effectiveness for precise results.
  2. Understanding the Accuracy of Estimated GFR: Factors and Insights Explore how accurate estimated GFR is for assessing kidney function and the factors that affect its reliability.