Are the Direwolves in Game of Thrones CGI?

Related questions

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6. Was CGI used in Star Wars?
7. What software is used for CGI?
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14. #direwolves
15. #animation
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17. #beasts
18. #season
19. #television
20. #puppies
21. #canids
22. #through
23. #universe
24. #portrayed